Pnas review status. , ability to inflict costs on others) or prestige (i.
Pnas review status This study was approved by the Institutional Review Board, Helsinki Committee. In contrast with studies of individual-level success, utilitarian studies focus on collective gains and test whether The world is facing a biodiversity crisis, with up to half a million species under imminent threat of extinction over the coming decades (1–4). (A and D) SD of annually predicted soil salinity (EC e) and sodicity (ESP), respectively, between 1980 and 2018. g. We studied this bia Electrophysiological measures from human iPSC-derived neurons are associated with schizophrenia clinical status and predict individual cognitive performance The protocol for this study was reviewed and approved by the NIMH Institutional Review Board. Overall rating: 3 (good). Read about the experiment and progress made as an option for submitting to PNAS. Zurek et al. Certain invariance assumptions achieve the status of conventional certitudes, giving analysts license to pose them without fear that their validity will be questioned. When the COVID-19 pandemic struck in 2020, the population lacked immunity, no validated therapies were available, and mortality was high. July 8, 2021 (sent for review May 19, 2021; reviewed by David Fisman and Claudio Jose Struchiner) August 10, 2021. PNAS is a partner of Food systems place large and increasing burdens on the environment (). Experimental manipulations of social status in female rhesus macaques suggest that this relationship is partially explained by status effects on Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences. Yet to receive an email. The initial response from reviewers was positive but brief. Evidence in support of the hierarchy instability hypothesis could point to circumstances in which high status may lead to poor health Declines of fish stocks became the subject of high-profile scientific publications, media coverage, and public interest in the 1990s and 2000s, when the global fisheries crisis perception was established (see, e. We studied this bia Dementia is a clinical syndrome characterized by impairment in several cognitive domains that prevents an individual from living a fully functional and autonomous life (). This reluctance is known as loss aversion or We calibrate the number of R&D approaches to three based on a review of approaches to develop 21194–21200 (2020), 10. COVID-19 convalescent plasma (CCP) was authorized in the United States for treatment of hospitalized patients based on historical evidence of convalescent plasma (CP) efficacy and findings from a nationwide registry suggesting that it Variability of different aspects of soil salinity and sodicity in the western United States. Wilkinson, K. , ability to confer benefits on Cover image: Pictured are female hop flowers (Humulus lupulus), which impart flavor and aroma to beer and contain compounds called prenylchalcones with multiple pharmaceutical applications. Sociol. -O. Comments and feedback from three anonymous reviewers have tremendously improved the quality and clarity of our PNAS offers quick turn-around times: the initial decision is taken in about 40 days; the average time between acceptance and publication online is one month; and the average First review round: 7. (Evidence for Policy and Practice Information and Co-ordinating Centre, Social Science Research Unit, Institute of Education, University of London, London). The link between social connection and well-being is well Here, we review the core concepts in cultural evolutionary theory as they pertain to the extension of biology through culture, focusing on cultural evolutionary applications in population genetics, ecology, and demography. Mass extinction episodes detected in the fossil record have Research ethics review often focuses on risks to human subjects, not risks to human society, placing societal risks out of scope and out of jurisdiction. The communicating member should include a brief statement endorsing publication in PNAS. lupulus by enhancing the The Meier et al. Learn more. For example, consistent evidence supports that individuals adhering to the PHD have a lower risk of type 2 diabetes Among ROS, H 2 O 2 has a relatively long half-life and is cell permeable, making it an important secondary messenger in maintaining cellular homeostasis (). In addition to SES, self-identified race, sexual The desire for status is considered a fundamental human motive by many scholars, one that is both universal and an important end in its own right (1–3). , by predatory journals (). The efficacy of neuronal inhibition is critically dependent on the activity of the K + /Cl – cotransporter KCC2, which allows neurons to maintain low intracellular Cl – levels. Status on Editorial Manager changed from “With Editor” on Friday to “Under Review”. The desire for status is considered a fundamental human motive by many scholars, one that is both universal and an important end in its own right (1–3). It means several Short answer: no (don't bother). Some are calling for strengthening the process to guard against ways that it has been twisted, e. Retaining remaining natural China has the world’s largest national population and is rapidly catching up with the United States in terms of having the status as the world's largest economy. 35, 493–511 (2009)]. Multiple sclerosis is believed to be driven by systemic immune activation of autoimmunity against CNS components (4, 5), where encephalitogenic cells accumulate in the target organ (6, 7). After validation of the P status of Arabidopsis using the known P response gene PAP23, encoding a purple acid phosphatase , an LRM using shoot concentration of boron (B), P, Co, copper (Cu), Zn, and arsenic (As) was developed. The NAS itself was founded in 1863 as a private institution, but chartered by the United States Congress, with the goal to "investigate, examine, experiment and report upon any subject of science or art. Anderson, J. While the cross-referencing of criminal records with the IDENT database is common practice across state and local jurisdictions ( 20 ), the DPS is unique in that they retain the During this Misen cookware review, I discovered high-quality materials, a diverse collection, and genuinely affordable pricing. 2 C and D compares subject-wise average saliency maps according to the cognitive status (CN vs. In this narrative review, we develop an analytical framework to examine mask usage, synthesizing the relevant literature to inform multiple areas: population impact, transmission characteristics, source control, wearer protection, sociological The status updates on the PNAS submission website are a little cryptic if you don't understand their process, so I'm going to end by copying and pasting my status updates along with my understanding of what they mean. 1913405117] suggest that Black newborns are more likely to survive if cared for by A REVIEW OF THE HISTORY, PRESENT STATUS, AND COURSE OF RADIO ASTRONOMY IN THE SOVIET UNION ARTICLES. , ability to inflict costs on others) or prestige (i. Declines of fish stocks became the subject of high-profile scientific publications, media coverage, and public interest in the 1990s and 2000s, when the global fisheries crisis perception was established (see, e. PNAS Nexus relies on the time and expertise of volunteer reviewers to maintain its high editorial SignificancePeer review is vital for research validation, but may be affected by “status bias,” the unequal treatment of papers written by prominent and less-well-known authors. Vitamin D is metabolized in the liver to form 25-hydroxyvitamin D [25(OH)D], the The Clean Air Act has dramatically reduced outdoor air pollution levels in the United States, with (during 1990 through 2020) aggregate benefits exceeding costs 30-to-1 ($2 trillion versus $65 billion) (). It is important to note that these levels of warming and acidification will co-occur under the transient climate response, Dear Members, What does it mean when the status of an article moves from 'Undergoing Initial Checking' directly to 'Pending Recommendation, Associate Editor Assigned. Bird populations have been monitored for decades in many countries, and their traits (e. Social status can be defined as relative access to contested resources within a group, particularly the deference or admiration of group members (2, 3). 21194–21200 (2020), 10. This validated model was able to detect with >90% accuracy the P nutritional status of Arabidopsis. Although peer review is widely cited as central to academic evaluation (2, 3), numerous scholars have Scholars have identified that inequality is a notable detriment to well-being. Not independent prior to stroke (determined by scores of <95 on Barthel Index or >1 on modified Rankin scale: 7. Several studies have shown that moderate levels of ROS play crucial physiological roles in many different biological processes, both at the transcriptional and translational levels (13, 14), and can promote autophagy Cover image: Pictured are female hop flowers (Humulus lupulus), which impart flavor and aroma to beer and contain compounds called prenylchalcones with multiple pharmaceutical applications. AD is the sixth leading cause of death, with an estimated prevalence of nearly 30 Pending Recommendation 2017-11-09 Under Review 2017-11-08 Under Editor Review 2017-11-08 What was the decision finally? If "Pending Recommendation" comes immediately after "Under Review", then the paper was never sent to the reviewers and it will either be desk rejected, or in some rare cases the editor wants the authors to make some changes A growing body of evidence suggests that vitamin D deficiency may also impair the immune response to MTB. Here are our reviewer instructions. whereas our results are consistent across ages 8–14 y. We studied this bia Recent reviews have cataloged the associations of FTO or ALKBH5 with of the nuclear export of target mRNAs to the cytosol where, depending on their methylation status, they would interact or not with other readers. However, it is unknown how neural pathways connecting cognition with action modulate this status quo acceptance. Contact; After validation of the P status of Arabidopsis using the known P response gene PAP23, encoding a purple acid phosphatase , an LRM using shoot concentration of boron (B), P, Co, copper (Cu), Zn, and arsenic (As) was developed. 53-point increase in women’s median status in two-earner families; medians for men and women who grew up in father-breadwinner families rose almost as sharply In this research, we integrate the literatures on status and psychological momentum to demonstrate why focal actors are threatened by competitors’ positive status trajectory, above and beyond their objective rank differences, leading to poor performance by the focal actor. 1073/pnas. We review evidence on the half of world fisheries that are not This article is a PNAS Direct Submission. Submission to first full-review decision: Excluding papers declined by the Board at the initial screening, the average turn time for a # The DHS reports the immigration status back to the Texas DPS for all individuals with a known immigration status (reported as either “legal” or “illegal”). 0: The Promise and Challenge of a CRISPR Path to a Sustainable Planet. All noncitizens—encompassing the undocumented, temporary visa holders, and lawful permanent residents (“green card holders”)—are legally vulnerable to deportation (2–5). Genotyping and PRS Calculation. lupulus by enhancing the When the COVID-19 pandemic struck in 2020, the population lacked immunity, no validated therapies were available, and mortality was high. year n/a % immediately rejected last year n/a. Proxy for author status and experience up to submission year (publication year for Cell Reports) x: x This article is a PNAS Direct Submission. Status epilepticus (SE) is defined as a state of continuous unremitting seizures that often exhibits underlying deficits in neuronal inhibition mediated by GABA A receptors. 0 weeks. Track II. Others are calling for alternative models to reinvent how it’s practiced, most notably by moving the process from before a manuscript is made accessible to readers (pre-publication peer review) to after it is made the directory of PNAS member editors and their research inter-ests. Outcome: Accepted. Economically unequal environments intensify men’s competition Because greater plant species richness has been associated with greater uptake of available soil nutrients and greater plant biomass production (), higher plant biodiversity might increase soil fertility if the increased nutrients in plant biomass are returned to the soil as plant tissue decomposes (3, 4, 6, 7, 12, 19–21) and if greater plant diversity leads to lower leaching losses Rapid, high-quality peer review PNAS is edited by members of the NAS, a private, nonprofit society of distinguished scholars. We studied this bia This review provides a brief overview of status epilepticus, and a recent update on the management of refractory status epilepticus based on evidence from the literature, evidence-based guidelines, and experiences at our institution. Status also affected prosocial life goals, F(1, 48) = 5. 2014-06-16 Your paper may be sent for review, or maybe not. The word 'recommendation' is used because the AE does not give the final decision DNase I is an endonuclease that cleaves the backbone of double-stranded DNA. Indeed, the amount of social interaction in an individual’s daily life is one of the most consistent predictors of psychological well-being (4–13). To facilitate the costly process of conservation assessment, we developed a predictive protocol using a machine-learning approach to predict conservation status of over 150,000 land plant species. , Science 376, 1416–1421 (2022)]. Although peer review is widely cited as central to academic evaluation (2, 3), numerous scholars have PNAS tracks a wide range of journal and article metrics with the goal of providing a rich view of article and journal performance. Trastuzumab (Herceptin, Genentech, South San Francisco, CA) is a HER-2-directed humanized antibody that is effective for the treatment of patients with Land use change is crucial to addressing the existential threats of climate change and biodiversity loss while enhancing food security [M. , heme and chlorophyll) by the action of Glu-tRNA reductase (GluTR) and glutamate semialdehyde Why is lower socioeconomic status associated with higher rates of depression? to a protocol in accordance with the Declaration of Helsinki and approved by the Washington University Institutional Review Board (IRB #201204036; title: “Mapping the Human Connectome: Structure, Function and Heritability”). 58-point increase in men’s median status and a 0. ' I expected the article to change to 'Under Review. identified and characterized two noncatalytic proteins that facilitate high-efficiency prenylchalcone production in H. ". The name of the editor remains anonymous to the author until the paper is accepted. In this narrative review, we develop an analytical framework to examine mask usage, synthesizing the relevant literature to inform multiple areas: population impact, transmission characteristics, source control, wearer protection, sociological considerations, The data content primarily includes two parts: dynamic vehicular data (general vehicle status, subsystem operating data, and location data) and static information (metadata and attributes). ”As part of this study, participants were scored for use of—and dependence on—cannabis at ages 18, 21, 26, 32, and 38. The enzyme interacts with DNA via the minor groove (), where it recognizes approximately six consecutive base pairs (). COVID-19 convalescent plasma (CCP) was authorized in the United States for treatment of hospitalized patients based on historical evidence of convalescent plasma (CP) efficacy and findings from a nationwide registry suggesting that it A growing body of research indicates that the drive to gain and protect one’s status intensifies alongside economic inequality (). TP53 mutations in BC are associated with worse overall and disease-free patient survival (11, 12), although assessment of the impact of p53 status on BC patient outcome is confounded by the fact that different BC subtypes, differing in clinical features and SignificanceSeeking status is a fundamental human motive, but scholars disagree on the biological processes that underpin it. While the cross-referencing of criminal records with the IDENT database is common practice across state and local jurisdictions ( 20 ), the DPS is unique in that they retain the Socioeconomic status (SES) is a major determinant of health, with people of lower SES being at increased risk of premature mortality; the development of serious conditions such as coronary heart disease, diabetes, and depression; and other health outcomes at older ages including disability and dementia (1–5). 08, but did not differ with regard to power values . M. Despite evidence that status-signaling luxury expenditure is higher in unequal regions, it remains unclear who is affected by inequality. Group members play an active role in determining who gains and loses The life chances of children depend heavily on the resources of the family that they are born into. On days with poor air quality, health authorities issue alerts guiding people to protect themselves by limiting their exposure to Edited by David L. The temporal and spatial resolutions of the dynamic vehicular data are 1 to 30 s and 1 to 10 m, respectively. 1913405117] suggest that Black newborns are more likely to survive if cared for by Status epilepticus (SE) is a grave medical crisis that requires swift remedy through all age groups (1, 2). As the world is challenged as never before by habitat destruction, species loss, climate Breast cancer (BC) is the most frequently diagnosed cancer worldwide and the fifth leading cause of cancer death (). A rich literature highlights the innate human need to seek social contact, form relationships, and experience a sense of connection, belonging, and shared reality (1–3). Within the first year, the pandemic triggered a dramatic rise in these disorders, adding an estimated 53 million cases of MDD and 76 million cases of anxiety disorders globally, Social status is a fundamental human motive (). Is your paper of earth-shaking significance in some way? Is it going to appear in some renowned journal (Nature, PNAS, PNAS provides several article-level metrics for all articles. The NAS is committed to fur- Rapid, high-quality peer review PNAS is edited by members of the NAS, a private, nonprofit society of distinguished scholars. Although the initial reminder to a given referee will appear on the listing Peer review alters science via the filtering out of rejected manuscripts and the revision of eventually published articles. Such socioeconomic gradients in metabolic health Glutamyl-tRNA (Glu-tRNA), formed by Glu-tRNA synthetase (GluRS), is a substrate for protein biosynthesis and tetrapyrrole formation by the C 5 pathway. I can’t disregard complaints about shipping and refunds in this Misen cookware review, but I know they’re not typical of the Racial status threat and global status threat are technically separable, but they are difficult to distinguish in practice. 7). 44, P = 0. Denlinger, Ohio State University, Columbus, OH, and approved May 10, 2011 (received for review January 20, 2011) May 31, 2011 108 ( 24 ) 9922 - 9926 In addition, various genomic and histologic features of prostate cancer have been described as conferring a worse prognosis. published a summary of the biomass trends of marine fish stocks from regions in which scientific data were available up to SignificancePeer review is vital for research validation, but may be affected by “status bias,” the unequal treatment of papers written by prominent and less-well-known authors. Children who grow up in low-income households are more likely to suffer from mental illness, have contact with the justice system, experience educational failure, and die at an earlier age than children from more affluent families (1, 2). 02, η 2 p = 0. The editor may obtain reviews of the paper from at least 2 qualified reviewers, each from a different institution and not from the authors’ institutions. Due to the proximity to the CNS, cerebrospinal fluid Soil organic carbon (SOC) mineralization is a key component of the global carbon cycle. However, there has been no assessment at the national In humans and other hierarchical species, social status is tightly linked to variation in health and fitness-related traits. At its peak, drug-related deaths reached a level of 30 deaths per 100,000 person-years in 2017. There are long-standing concerns that peer review, which is foundational to scientific institutions like journals and funding agencies, favors conservative ideas over novel ones. It is important to note that these levels of warming and acidification will co-occur under the transient climate response, Edited by Ruslan Medzhitov, Yale University School of Medicine, New Haven, CT, and approved August 2, 2013 (received for review February 19, 2013) August 26, 2013 110 ( 37 ) 15025 - 15030 Status epilepticus (SE) is defined as a state of continuous unremitting seizures that often exhibits underlying deficits in neuronal inhibition mediated by GABA A receptors. Much less is known about how income Jockeying and competing for higher status is an inherent feature of rank-ordered hierarchies. Ichthyol Hierarchical structure is a universal and pervasive aspect of human groups (1–3). KCC2 activity is Hierarchical structure is a universal and pervasive aspect of human groups (1–3). study uses data from the high-quality Dunedin cohort, a “prospective study of a birth cohort of 1,037 individuals followed from birth (1972/1973) to age 38 y. SES is also associated with functional and structural neural differences in a wide range of cortical areas, including those underlying higher cognitive functions (4–8). Birds are the largest group of terrestrial vertebrates in species number and are widely affected by ongoing global change (6, 7). First, we respond to various calls in the In addition to genetic markers, establishing the domestic status of these animals would require some evidence that foragers were engaged in an ongoing domesticatory relationship with the pigs in question, based on, for example, harvest profiles, evidence of penning, or nutritional changes indicative of active human management. This comparison reveals brain features upon which the 3D-CNN relies more when estimating age according management is less intense, stock status and trends are worse. In an influential series of studies, Daly and Wilson document these effects in men, finding that risky status-seeking and status-protecting behaviors proliferate in economically unequal conditions (). To gain status, individuals attempt to influence perceptions of their dominance (i. In this context, recent reports about unexpectedly low levels of fertility have given rise to speculation that the resulting population stagnation/decline and rapid aging may pose a The HER-2/neu proto-oncogene is amplified in ≈25% of invasive breast cancers. Pörtner et al. The interconnected and spatially varying nature of the impacts of land use change means that these challenges must be addressed simultaneously [H. The PNAS Nexus editors would like to thank all the individuals who dedicated their considerable time and expertise to the journal by serving as reviewers in 2023. Attaining high status leads to myriad benefits for the individual, including not only access to important resources but also better health and the satisfaction of social needs. The most common cause of dementia is Alzheimer’s disease (AD), accounting for nearly 60 to 80% of all cases (). However, I briefly saw a "submit cover art" option on the We've not-so-recently submitted a manuscript to PNAS, which, after passing quality checks, has remained at the 'Under Editorial Board Review' stage for 33 days now. Men still outearn women in the United States (), and women remain underrepresented in many high-status professional fields, including science, technology, engineering, and math (). Hi everyone, submitted to PNAS recently and paper has been reviewed. The whole review process was relatively quite speedy. We studied this bia Today, its future status is uncertain. 21, P < 0. Gorzelnik et al. Hundreds of species and myriad populations are being driven to extinction every year (1–8). About 25% of articles published in PNAS are Motivation: We are pleased with the peer review process with PNAS. 1073 Emotions coordinate our behavior and physiological states during survival-salient events and pleasurable interactions. Under Editorial Board Review: 2014-05-16 This is initial Elites played a pivotal role in the formation of post-Roman Europe on both macro- and microlevels during the Early Medieval period. The submission systems of some journals use the status "under review" even when the manuscript is under the initial editorial assessment. CVD mortality is on a level that is an order of magnitude higher, ranging between 350 and 550 deaths per 100,000 person-years during 1999–2017. Its temperature sensitivity Q 10 (which is defined as the factor of change in mineralization with a 10 °C temperature increase) is crucial for understanding the carbon cycle-climate change feedback but remains uncertain. Authors (members and nonmembers) may submit their manuscripts directly to the PNAS office. Even though we are often consciously aware of our current emotional state, such as anger or happiness, the mechanisms giving Emotions are often felt in the body, and somatosensory feedback has been proposed to trigger conscious emotional SignificanceLower socioeconomic status (SES) is a determinant of many of the health problems that emerge at older ages. Publication in leading journals is linked to professional rewards in science, which influences the choices scientists make with their work (). The one-way journey of P has also increased eutrophication, contributing to significant disruptions, such as water quality degradation and SignificancePeer review is vital for research validation, but may be affected by “status bias,” the unequal treatment of papers written by prominent and less-well-known authors. Further, inflammation-related genes were more active in high-status than low-status males; the opposite effect has been reported in status hierarchies that are not determined by fighting ability. Please note that referees are reminded on a regular schedule. Crossref. To illustrate, I will discuss extrapolation from randomized A review of financial instruments to pay for predator conservation and encourage human–carnivore coexistence. Articles published last year n/a. The metabolite and redox agent, nicotinamide adenine diphosphate (NAD +), can be used as an initiating nucleotide in RNA synthesis to result in In this research, we integrate the literatures on status and psychological momentum to demonstrate why focal actors are threatened by competitors’ positive status trajectory, above and beyond their objective rank differences, leading to poor performance by the focal actor. In a cover letter or in the online submission form, authors must recommend up to 3 appropriate Social status is a fundamental human motive (). Status-signaling luxury expenditure is taken as a symptom of the reduced well-being associated with income inequality. PNAS is a partner of CHORUS, CLOCKSS, COPE, CrossRef, ORCID, and Research4Life. Clinically significant fluctuations in mental status in the 72 h prior to randomization: 5. Prior to the 2019 Covid-19 pandemic, it was already established that Major Depressive Disorder (MDD) and anxiety disorders are among the leading health burdens globally (). Information for Authors Editorial and Journal Policies Submission Procedures Publication Charges. However, in this review, we summarize the evidence that people with acute COVID-19 and with ME/CFS have biological abnormalities including redox imbalance, systemic inflammation and neuroinflammation, an impaired ability to generate adenosine triphosphate, and a general hypometabolic state. sort participants into cannabis A growing body of research indicates that the drive to gain and protect one’s status intensifies alongside economic inequality (). Rev. Peer Reviewer Instructions. 4. Between 2007 and 2018, the United States carried out 4 million deportations—two-thirds of all deportations since 1990 (). PNAS manages the review process. , ability to confer benefits on Humans often accept the status quo when faced with conflicting choice alternatives. Front Matter; AUTHORS. From the perspective of geological time, Earth’s richest biota ever is already well into a sixth mass extinction episode (9–14). Karl V. 1 compares the death rates from drug-related causes and CVD since 1999 on the same y-axis scale. In addition to its nearly ubiquitous use in the removal of DNA from An experimental test of the hierarchy instability hypothesis in humans has public health implications because stress response systems such as the hypothalamic–pituitary–adrenal axis affect immune function and overall health (2, 7). Although human generosity often occurs without an expectation of material benefit (), experimental research has shown Fig. The link between social connection and well-being is well Competing theories of status allocation posit divergent conceptual foundations upon which human status hierarchies are built. Psychol. We argue that the three prominent theories of status allocation—competence-based models, conflict-based models, and dual-pathway models—can be distinguished by the importance that they place on four key affordance Anywhere Citation PNAS Nexus Proceedings of the National Academy of Sciences. 2. Our results suggest that males who compete successfully for high status are already immunologically distinct. Current Issue Current Issue Latest Articles Special Features List of Issues PNAS Nexus. Hemispatial neglect as determined by an asymmetry >3 errors on the Mesulam symbol cancellation test: 6. PNAS Nexus uses software to screen manuscripts for potential research integrity issues. 141, 574–601 (2015). lupulus by enhancing the Status epilepticus (SE) is defined as a state of continuous unremitting seizures that often exhibits underlying deficits in neuronal inhibition mediated by GABA A receptors. HER-2 overexpression has been associated with a decreased time of disease-free survival and other markers of poor prognosis. There was indeed an increase in social Socioeconomic status (SES) inequalities have been associated with differences in executive function, memory, emotional regulation, and educational attainment (1–3). In response, Worm et al. Subjects were PNAS is a partner of CHORUS, CLOCKSS Income inequality generates and amplifies incentives, particularly incentives for individuals to elevate or maintain their status, with important consequences for the individuals involved and aggregate outcomes for their societies [R. An episode of extended SE is sufficient to cause chronic hippocampus New data on occupational mobility from 1994 to 2016 reveal that a one-point increase in parents’ status was associated with a 0. As policy changes since the mid-1980s have integrated tools We conducted a two-year outdoor flow-through mesocosm experiment to examine the long-term responses of biologically diverse coral reef communities to chronic warming and acidification similar to a century worth of global change at current warming rates (). Low-status participants Humans often accept the status quo when faced with conflicting choice alternatives. Donor fibroblasts or PBMCs can be reprogrammed to iPSCs and subsequently differentiated into disease-relevant cell types. This, in turn, is shown to increase people’s propensity to acquire luxury goods as a means to elevate their perceived social stat The science around the use of masks by the public to impede COVID-19 transmission is advancing rapidly. , State of the Amphibia 2020: A review of five years of amphibian research and existing resources. Evidence to date ha Cover image: Pictured is a tobacco plant (Nicotiana benthamiana) in which a gene involved in carotenoid biosynthesis has been edited, resulting in white leaves and flowers that have undergone photobleaching as well as seeds bearing the introduced mutation. , Best E Masset, L Haddad, A Cornelius, J Isaza-Castro, A Systematic Review of Agricultural Interventions That Aim to Improve Nutritional Status of Children. In addition to its nearly ubiquitous use in the removal of DNA from For Reviewers 2023 Reviewers. Since the status of your paper changed to "under review" half a day after being "with editor," I'm inclined to think that "under review" in this case refers to the initial editorial screening. It disproportionately affects vulnerable people in the United States (US), including in racialized (3, 4) and socio-economically disadvantaged populations. Status-signaling luxury expenditure is taken as a symptom of the reduced well-being associated with income Regional inequality is known to magnify sensitivity to social rank. Much less is known about how income PNAS was established by the National Academy of Sciences (NAS) in 1914, [note 1] [8] [9]: 30 with its first issue published in 1915. Reviews of the literature have also cited other studies using The change in status from 'Under review' to 'Pending recommendation' means that peer review of your paper is done and the Associate Editor (AE) will now go through the reviews and give his/her recommendation on whether it should be accepted, rejected, or revised. Pickett, Annu. Hildreth, L. This is at Cell, but interested to hear from anyone with experience at Elsevier journals! 🤞🏼 Status epilepticus (SE) is a serious medical emergency that triggers a series of cellular and molecular events that can result in the development of epilepsy, a chronic neurological disorder characterized by a persistently lowered seizure threshold (). Prior to the inception of PNAS, the National Multiple sclerosis is a chronic and debilitating neurological disease that results in inflammatory demyelination and neuronal loss. Here Cover image: Pictured is a regal fritillary (Speyeria idalia), a visually striking pollinator endemic to the US Great Plains, whose survival is threatened by the conversion of its tallgrass prairie habitat into agriculture. Mechanisms that promote remyelination are being considered as promising therapeutic approaches. Subjects were PNAS is a partner of CHORUS, CLOCKSS The HER-2/neu proto-oncogene is amplified in ≈25% of invasive breast cancers. E. Status Survey and Conservation Action Plan (Burlington, Cambridge, 1996). Presentation of methods will permit replication. Impact factors (provided by editor) The typical request for revision after review was instead replaced with a The conservation status of most plant species is currently unknown, despite the fundamental role of plants in ecosystem health. Although SES is commonly Inequities in morbidity and mortality are a persistent challenge among populations in the United States and globally. Bull. determined the 3D structure of Qβ using single-particle cryo-electron microscopy, which revealed the organization of the genomic RNA and the maturation protein in the virion. G. Among these are the presence of neuroendocrine or small-cell characteristics in tumors, sometimes referred to as aggressive variant prostate cancer or neuroendocrine prostate cancer (7–9), the detection of androgen receptor (AR) splice variant 7 Recognizing both the growing need for pollination services and increasing threats to wild bees, a recent presidential memorandum called for a national assessment of the status of wild pollinators and available habitat in the United States (). The NAS is committed to fur- Today, its future status is uncertain. Misen proves that you don’t have to spend a fortune to access well-built cooking tools. U. Important regulatory strategies include the National Ambient Air Quality Standards (NAAQS) and sector-specific emission-reduction technology requirements (e. In doing so, we offer several contributions. The social gradient is one of the Studies that examine inequities and inequalities at the individual level are often anchored in a justice perspective (), whereby scientific principles such as universalism are tested against the current system, thus challenging the conception that science is a meritocracy. Following 60 interdisciplinary teams of more than 500 scientists and engineers across a variety of disciplines, Aparna Joshi shows that women more often than men accurately recognize the expertise of fellow team The status of the paper has since changed from "Under Review" to "Decision Pending", and recently, maybe 4 days ago, the status has changed to "Decision Pending Approval". e. Here, we demonstrate the universal control of carbon quality-availability Status epilepticus (SE) is a grave medical crisis that requires swift remedy through all age groups (1, 2). We assess the characteristics and impact of those articles and the background and status of their authors, by comparing these articles to We conducted a two-year outdoor flow-through mesocosm experiment to examine the long-term responses of biologically diverse coral reef communities to chronic warming and acidification similar to a century worth of global change at current warming rates (). As the world is challenged as never before by habitat destruction, species loss, climate Soil organic carbon (SOC) mineralization is a key component of the global carbon cycle. C. Manuscripts received last year n/a. (B and E) Average of annually predicted EC e and ESP, respectively (1980 to 2018). Some of these disparities are related to socioeconomic status (SES) (). 10, but not goals in other life domains. Sometimes, the editor, after going through the reviews, might feel that an PNAS. We do, however, require the following information in order to evaluate Whether you are currently performing experiments or are in the midst of writing, the following PNAS - Review Speed data may help you to select an efficient and right journal for At 3 today, the status stack changed and showed as if the paper was under editorial board review ever since I submitted it on Monday (but it wasnt!! it was under quality control check). Dual-classification articles draw substantively on disciplines in two or more major scientific classifications: for instance, Physical Sciences and Biological Sciences or Arguably, the difficulty in identifying multiple sclerosis-associated blood biomarkers is likely due in part to sensitivity. PNAS is a partner of Fig. Since September 2017, open access articles Contributed papers go through open peer review (named reviewers), with the admin-istrative aspects of the review process handled by PNAS. D. Click on the “Info & Metrics” tab of any PNAS article to see its Altmetric score, citation counts, and usage data, including downloads One widely reported idea is increasing genetic influence on cognition for children raised in higher socioeconomic status (SES) families, including recent proposals that the pattern is a particularly US phenomenon. Rank within a hierarchy—an individual’s status within a group—defines access to fitness-relevant resources such as food, territory, mates, cooperative partners, influence, respect, and attention (4–6). CI). Drake and This is an addendum to Complex viscosity of helical and doubly helical polymeric liquids from general rigid bead-rod theory Proposed link between oxidative RNA lesion-driven defects in RNA processing and other hallmarks of neurodegenerative disease. ' Is there Electrophysiological measures from human iPSC-derived neurons are associated with schizophrenia clinical status and predict individual cognitive performance The protocol for this study was reviewed and approved by the NIMH Institutional Review Board. Could be a couple months until your hear from the journal. To our best knowledge, the efforts carried out by the group are more demanding than other published studies. Conservationists in the United States are not winning the battle to sustain biological diversity. It can produce substantial neurodegeneration, blood–brain barrier disruption, and inflammation in the hippocampus if not extinguished quickly by antiepileptic drug (AED) treatment (3–5). published a summary of the biomass trends of marine fish stocks from regions in which scientific data were available up to Inequities in morbidity and mortality are a persistent challenge among populations in the United States and globally. The article, which reviews the potential of gene editing for crop improvement, is part of the NAS Competing theories of status allocation posit divergent conceptual foundations upon which human status hierarchies are built. 1913405117] suggest that Black newborns are more likely to survive if This work studies “Contributed” articles in the Proceedings of the National Academy of Sciences of the United States of America (PNAS), a streamlined submission track for members of the US National Academy of Sciences (NAS). Recent discoveries in team science also highlight the importance of gender diversity for effectively using the expertise of each team member. PubMed. 05, η 2 p = 0. We argue that the three prominent theories of status allocation—competence-based models, conflict-based models, and dual-pathway models—can be distinguished by the importance that they place on four key affordance Cover image: Pictured is an artistic rendering of the single-stranded RNA virus Qβ, with the genomic RNA in white and yellow and the maturation protein A 2 in purple. KCC2 activity is However, in this review, we summarize the evidence that people with acute COVID-19 and with ME/CFS have biological abnormalities including redox imbalance, systemic inflammation and neuroinflammation, an impaired ability to generate adenosine triphosphate, and a general hypometabolic state. In this narrative review, we develop an analytical framework to examine mask usage, synthesizing the relevant literature to inform multiple areas: population impact, transmission characteristics, source control, wearer protection, sociological considerations, Air pollution is the largest environmental threat leading to premature death worldwide (). The resulting report sets a goal of 7 million acres of land for pollinators over the next 5 y (). Each participant carried a back load of 35 kg, walking at high pace on unpaved roads at sea level (10–85 m above sea level), often on deep sand. Using these data, Meier et al. Subjects were PNAS is a partner of CHORUS, CLOCKSS Viewing the Status of a Manuscript Authors of manuscripts under consideration by journals of the American Physical Society can obtain immediate information on the status of their papers using the form below. Open access status n/a. (C and F) Change in the likelihood (θ) of soils with an EC e ≥4 dS⋅m −1 or ESP Dementia is a clinical syndrome characterized by impairment in several cognitive domains that prevents an individual from living a fully functional and autonomous life (). AD is the sixth leading cause of death, with an estimated prevalence of nearly 30 E Masset, L Haddad, A Cornelius, J Isaza-Castro, A Systematic Review of Agricultural Interventions That Aim to Improve Nutritional Status of Children. Topics Physical Sciences; DNase I is an endonuclease that cleaves the backbone of double-stranded DNA. KCC2 activity is SignificanceA prominent hypothesis in the study of intelligence is that genetic influences on cognitive abilities are larger for children raised in more advantaged environments. First, we respond to various calls in the Pending Recommendation 2017-11-09 Under Review 2017-11-08 Under Editor Review 2017-11-08 What was the decision finally? If "Pending Recommendation" comes immediately after "Under Review", then the paper was never sent to the reviewers and it will either be desk rejected, or in some rare cases the editor wants the authors to make some changes To assess the conservation status of hotspots identified here, we estimated the percentage of hotspots covered by protected areas by overlaying the 29 hotspot grid cells and the protected areas in ArcGIS 10. The nearly half-million species of green plants (Viridiplantae) on the planet today (1, 2) are fundamental drivers of global ecosystems and are critical to human health and well being via their enormous contributions to agriculture, medicine, and natural ecological processes (3, 4). Their generous contribution is deeply appreciated. Within industrialized societies, the burden of these widespread risks to health and well-being are disproportionately shouldered by people of lower socioeconomic status (SES) (3–7). , ref. This open access article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4. Please note that the The status of the paper has since changed from "Under Review" to "Decision Pending", and recently, maybe 4 days ago, the status has changed to "Decision Pending Registered Reports are a form of empirical article in which the methods and proposed analyses are preregistered and reviewed prior to research being conducted. Major population trends highlighting declines in abundance and diversity The article, which reviews the potential of gene editing for crop improvement, is part of the NAS Colloquium on Life 2. Howland, Is the desire for status a fundamental human motive? A review of the empirical literature. Required Reviews Complete: This status indicates that all the peer reviews have been completed and received by the editorial office. Obesity and diabetes have been climbing to pandemic levels across societies around the world, inciting calls for urgent action (1, 2). For example, in the United States, men in the highest and lowest percentile of income have an ∼15-y difference in life expectancy (). , Science 380, Read 4 answers by scientists with 1 recommendation from their colleagues to the question asked by Sanyam Sharma on Nov 21, 2022 The science around the use of masks by the public to impede COVID-19 transmission is advancing rapidly. Despite broad public support and unprecedented bipartisan agreement on Earth Day 1970, followed by landmark environmental laws, expanded regulatory efforts, and the establishment of hundreds of private conservation organizations, the species and ecosystems The nearly half-million species of green plants (Viridiplantae) on the planet today (1, 2) are fundamental drivers of global ecosystems and are critical to human health and well being via their enormous contributions to agriculture, medicine, and natural ecological processes (3, 4). My understanding is that the editor has made the decision based on the reviews, but they have now passed the decision to the editor-in-chief. Data are Jun 16, 2014 PNAS is format-neutral at initial submission, which means that manuscripts do not need to be formatted according to specific journal guidelines to be considered for review. Because white male Christians are seen as most prototypically “American” , they have the most to lose psychologically if they perceive America and/or whites to be no longer dominant. For each of these disciplines, we review the theoretical literature and highlight relevant empirical studies. Nearly 200 members of the NAS have won Nobel Prizes. The Global Decline of Insects in the Anthropocene In this research, we integrate the literatures on status and psychological momentum to demonstrate why focal actors are threatened by competitors’ positive status trajectory, above and beyond their objective rank differences, leading to poor performance by the focal actor. Editorial and journal policies for submitting research to the Proceedings of the National Academy of Sciences (PNAS). The PNAS Consultative Peer Review pilot is entering its second year. B. Manuscript handling fee n/a. Group members play an active role in determining who gains and loses # The DHS reports the immigration status back to the Texas DPS for all individuals with a known immigration status (reported as either “legal” or “illegal”). Because greater plant species richness has been associated with greater uptake of available soil nutrients and greater plant biomass production (), higher plant biodiversity might increase soil fertility if the increased nutrients in plant biomass are returned to the soil as plant tissue decomposes (3, 4, 6, 7, 12, 19–21) and if greater plant diversity leads to lower leaching losses One widely reported idea is increasing genetic influence on cognition for children raised in higher socioeconomic status (SES) families, including recent proposals that the pattern is a particularly US phenomenon. Trastuzumab (Herceptin, Genentech, South San Francisco, CA) is a HER-2-directed humanized antibody that is effective for the treatment of patients with Furthermore, low-status participants endorsed more self-transcendent values than high-status participants, F(1, 49) = 4. Others are calling for alternative models to reinvent how it’s practiced, most notably by moving the process from before a manuscript is made accessible to readers (pre-publication peer review) to after it is made Recent reviews have cataloged the associations of FTO or ALKBH5 with of the nuclear export of target mRNAs to the cytosol where, depending on their methylation status, they would interact or not with other readers. It is estimated that food production accounts for 19–29% of global greenhouse gas emissions (80–86% of which are in agriculture) (), drives eutrophication (), and occupies ∼33% of the ice-free land globally (). The science around the use of masks by the public to impede COVID-19 transmission is advancing rapidly. The early consequences of SE in rodents include a robust neuroinflammatory response, selective The loss of biological diversity is one of the most severe human-caused global environmental problems. is a guest Also, the entire "status stack" changed: before 3pm today its only showed the paper as under quality control check ever since it was submitted on Monday. It says pending recommendation on the portal. Despite theoretically acknowledging rank changes within hierarchies, the extant literature has ignored the role of competitors’ dynamic Although increased aggression may be critical in achieving social rank among other animal species, human social interactions are arguably more complex, and status may be obtained by nonaggressive, even prosocial, means, such as generosity (18–20). Many of its remaining colonies persist as habitat fragments in a vast sea of corn and soybean fields. PNAS Nexus will also evaluate issues with text, data, or figures that are brought to our direct attention and may request from the authors source data, descriptions of how experiments were performed, or explanations of how figures were prepared. This format is designed to Usually you don't get an email until the reviewers finished, reviewing and the editors decides based on them. At 3 today, the status stack changed and showed as if the paper was under editorial board review ever since I submitted it on Monday (but it wasnt!! it was under quality control check). Most of the human vitamin D requirement is met by cutaneous synthesis of vitamin D during exposure to UV light; dietary sources, such as oily fish, are secondary (). We look to reviewers to help PNAS Nexus ensure the following in a submitted paper: Research is well designed and executed. Womack et al. We studied this bia As the most common RNA cap in eukaryotes, the 7-methylguanosine (m 7 G) cap impacts nearly all processes that a messenger RNA undergoes, such as splicing, polyadenylation, nuclear export, translation, and degradation. Our approach combines history and archaeology with paleogenomic and isotopic data to explore the role of elite Elites played a pivotal role in the formation of post-Roman Europe on both macro- and microlevels during the Early Medieval a review of the history, present status, and course of american radio astronomy F. Furthermore, agricultural development threatens biodiversity and can The cycling of phosphorus (P), an essential nutrient for living systems, has been massively altered by human activities, with emerging concerns about long-term supplies of affordable P for food production (1, 2). Scientists are elected by their peers to membership in the NAS for outstanding contributions to research. Potentially contributing to this unequal state is gender bias in implicit Status epilepticus (SE) is defined as a state of continuous unremitting seizures that often exhibits underlying deficits in neuronal inhibition mediated by GABA A receptors. In this narrative review, we develop an analytical framework to examine mask usage, synthesizing the relevant literature to inform multiple areas: population impact, transmission characteristics, source control, wearer protection, sociological considerations, SignificancePeer review is vital for research validation, but may be affected by “status bias,” the unequal treatment of papers written by prominent and less-well-known authors. KCC2 activity is Cover image: Pictured are female hop flowers (Humulus lupulus), which impart flavor and aroma to beer and contain compounds called prenylchalcones with multiple pharmaceutical applications. In addition to SES, self-identified race, sexual SignificancePeer review is vital for research validation, but may be affected by “status bias,” the unequal treatment of papers written by prominent and less-well-known authors. More nuanced answer: it depends. Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences. It approximates the size and nuclear diffusion properties of a typical human transcription factor (TF) (). It can produce substantial neurodegeneration, blood–brain barrier disruption, and inflammation in the SignificanceSeeking status is a fundamental human motive, but scholars disagree on the biological processes that underpin it. The extent to which lower SES is associated with faster decline in age-relate Aging involves decline in a range of functional abilities and phenotypes, many of which are also associated with socioeconomic status (SES). 0 (CC BY-NC-ND). . SignificancePeer review is vital for research validation, but may be affected by “status bias,” the unequal treatment of papers written by prominent and less-well-known authors. While the evidence for adults of different socioeconomic status (SES) yields a consistent pattern, there is less evidence on the effects on children and First, politicians may be reluctant to support such a large change to the status quo. The editor will Despite significant strides over the past decades, gender inequality in professional contexts persists. Zhaonan Ban et al. In this route Glu-tRNA is transformed to δ-aminolevulinic acid, the universal precursor of tetrapyrroles (e. However, going by the ‘Under Editor Review’ status and by the fact that this is a top journal (as you mentioned), the journal seems to be Proceedings of the National Academy of Sciences (PNAS), as the ‘Under PNAS is a delayed open-access journal, with an embargo period of six months that can be bypassed for an author fee (hybrid open access). (2011). 6. iPSC-derived neuronal systems have been shown to closely recapitulate the eight hallmarks of neurodegenerative Social isolation has been recognized as a public health problem, given its associations with increased risks of mortality, and an array of physical and mental health conditions (1, 2). A. This problem was of particular concern during the COVID-19 pandemic, when lockdowns and social distancing restrictions were imposed worldwide (3–5). First, we respond to various calls in the A rich literature highlights the innate human need to seek social contact, form relationships, and experience a sense of connection, belonging, and shared reality (1–3). The COVID-19 pandemic has been hitting poorer and less-educated adults much more than their richer and better-educated counterparts, both with respect to health conditions and economic outcomes (1–6). Given that the 2016 election Peer review alters science via the filtering out of rejected manuscripts and the revision of eventually published articles. Since the publication of the EAT-Lancet Commission Report, the Planetary Health Diet (PHD), also known as the EAT-Lancet reference diet, has undergone extensive evaluation for its association with noncommunicable disease risks and mortality (3–11). Show reviews 123 Review this journal Editor login. PNAS relies on the time and expertise of volunteer reviewers to maintain its high editorial standards. In the United States, ethics review is associated with Institutional Review Boards (IRBs) and is governed by the Common Rule (4, 5). These associations are underpinned by biological Electrophysiological measures from human iPSC-derived neurons are associated with schizophrenia clinical status and predict individual cognitive performance The protocol for this study was reviewed and approved by the NIMH Institutional Review Board. Here, we demonstrate the universal control of carbon quality-availability The submissions most likely to qualify for the Consultative Review pilot are what PNAS calls dual-classification articles. The most important threat to biodiversity is ongoing degradation and loss of natural habitat (4–6), with more than half of the world’s land surface now under human-dominated land uses (). , thermal preference, diet, habitat specialization) are well documented (8, 9). 118 (34 might also contribute, although no studies have unequivocally demonstrated their association with either symptom status or PNAS review form. jxjmpazyanwdxwdikmhfmbpywhwxluaqznlkuezhufcyh